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ORNITHINE CARBOXY-LYASE
Descriptors Found:
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DeCS
Descriptor
English
:
Ornithine Decarboxylase
Descriptor
Spanish
:
Ornitina Descarboxilasa
Descriptor
Portuguese
:
Ornitina Descarboxilase
Synonyms
English
:
Carboxy-lyase, Ornithine
Decarboxylase, Ornithine
Ornithine Carboxy lyase
Ornithine Carboxy-lyase
Tree Number:
D08.811.520.224.125.425
Definition
English
:
A pyridoxal-phosphate protein, believed to be the rate-limiting compound in the biosynthesis of
polyamines
. It catalyzes the
decarboxylation
of
ornithine
to form
putrescine
, which is then linked to a propylamine moiety of decarboxylated
S-adenosylmethionine
to form
spermidine.
Entry Combination - descr/qualif
English
:
Ornithine Decarboxylase
/
antagonists & inhibitors
use
Ornithine Decarboxylase Inhibitors
History Note
English
:
84(75); was see under CARBOXY-LYASES 1975-83
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
10133
Unique Identifier:
D009955
Occurrence in VHL
:
Similar:
DeCS